| 内容提要: |
Cerebralcare Granule（养血清脑颗粒）, one of the famous classical recipes in traditional Chinese medicin, is developed from the "Decoction of Four Drugs". It is able to ameliorate the detrimental effect on cognition following chronic cerebral hypoperfusion , improve cerebromeningeal microcirculation, inhibit platelet aggregation, and release vasospasm. Currently, the recipe is mostly used for treating headache, including migraine headache, neurogenic headache, etc.
Hypertension is a cardiovascular disease with the most epidemiological impact in the world and also represents a major risk factor for developing other diseases as endothelial dysfunction, metabolic syndrome, diabetes, renal dysfunction, congestive heart failure, coronary artery disease and stroke.
Worldwide hypertension is estimated to cause 7.1 million premature deaths and 4.5 % of the disease burden.
This report will present the pathogenesis of hypertension, mainly around the mechanism of vasodilatation.
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