| 内容提要: |
Over the past 28 years there have been several thousand publications describing the use of 2D NMR
to identify and characterize natural products. During this time period, the amount of sample needed
for this purpose has decreased from the 20–50 mg range to under 1 mg. This has been due to
both improvements in NMR hardware and methodology. This review will focus on mainly
methodology improvements, particularly in pulse sequences, acquisition and processing methods
which are particularly relevant to natural product research, with lesser discussion of hardware
improvements. |