| 内容提要: |
This study collected drinking water samples from seventy-one cities (twenty-eight provincial capital cities or municipalities, twenty prefecture cities and twenty-three counties) of thirty-one provincial-level administrative regions in China from July to August in 2017, and the abundance of twenty-four antibiotic resistance genes (ARGs), 16SrDNA and two integrons were quantified with qPCR to investigate the pollution level of ARGs. Moreover, the relationship evaluation between integrons and ARGs was conducted, and the inner relationship of GDP with ARGs was investigated. The results showed sulfonamides-ARGs were the most prevalent ARGs in drinking water of China, and the abundance of blaTEM was top five in all cities among all selected ARGs, indicating some bacteria might have multiple drug resistance (MDR). Correlation analysis results showed int1 played a more important role comparing to int2 in ARGs propagation in drinking water. In addition, GDP might be the key factor influencing ARGs pollution level in drinking water of China. |