研究生学术报告预告登记（开题、中期、答辩）

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报告人: 刘世鹏
学号: 2011213036
学院: 药物科学与技术学院
报告类型: 第一次学术报告
日期: 2 May 2012
时间:
地点: 24楼A区107
导师: 万谦宏
题目: Mesoporous Silica Templated Biolabels with Releasable Fluorophores for Immunoassays
内容提要: A novel class of fluorescent immuno-biolabeling systems
with extremely high F/P ratio (∼1000 6000) were
prepared by combining the template method and layer-
by-layer (LbL) technique. Labels were constructed by
loading organic dye fluorescein diacetate (FDA) molecules
onto hollow periodic mesoporous organosilica (H-PMO)
particles followed by ployelectrolyte encapsulation and
antibody attachment. The labeling systems were stimuli-
responsive to the addition of concentrated NaOH with the
loaded dye molecules being released and detected in a
well-controlled manner. When applied in sandwich im-
munoassays, results indicated that the biolabels were
immuno-active and generated an optimal signal that was
∼50 times higher than the conventional dye labelled
antibody system
图片:
登记人: 刘世鹏
登记时间: Sunday, 29 April 2012, 9:25 PM
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