Aryl halides are widely utilized in many areas as significant chemical materials and pharmaceutical intermediates. Different kinds of aryl halides, because of their different reaction activities, always have different versatility and could implemet diverse functional modifications.
Then, referring to the previous researches in our group, we firstly propose to develop analogous metal-catalyzed methods to obtain the chlorine or iodine-substituent compounds. Subsequently, we would explore other meta-subtitution reaction through an ortho-metalation strategy. |